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MLXIPL Antikörper (AA 18-143)

This anti-MLXIPL antibody (ABIN1724913) is a Mouse Monoclonal antibody detecting MLXIPL in ELISA, ICC. Suitable for Human.
Produktnummer ABIN1724913

Kurzübersicht für MLXIPL Antikörper (AA 18-143) (ABIN1724913)

Target

Alle MLXIPL Antikörper anzeigen
MLXIPL (MLX Interacting Protein-Like (MLXIPL))

Reaktivität

  • 37
  • 25
  • 13
  • 5
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 50
  • 2
Maus

Klonalität

  • 50
  • 2
Monoklonal

Konjugat

  • 24
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser MLXIPL Antikörper ist unkonjugiert

Applikation

  • 27
  • 15
  • 13
  • 13
  • 13
  • 10
  • 9
  • 8
  • 3
  • 3
  • 1
  • 1
  • 1
ELISA, Immunocytochemistry (ICC)

Klon

5D12D1
  • Bindungsspezifität

    • 15
    • 9
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 18-143

    Verwendungszweck

    MLXIPL Antibody

    Aufreinigung

    Ascitic fluid

    Immunogen

    Purified recombinant fragment of human MLXIPL (AA: 18-143) expressed in E. Coli.

    Isotyp

    IgG1
  • Applikationshinweise

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Ascitic fluid containing 0.03 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Noordeen, Meur, Rutter, Leclerc: "Glucose-induced nuclear shuttling of ChREBP is mediated by sorcin and Ca(2+) ions in pancreatic β-cells." in: Diabetes, Vol. 61, Issue 3, pp. 574-85, (2012) (PubMed).

    Hurtado del Pozo, Vesperinas-García, Rubio, Corripio-Sánchez, Torres-García, Obregon, Calvo: "ChREBP expression in the liver, adipose tissue and differentiated preadipocytes in human obesity." in: Biochimica et biophysica acta, Vol. 1811, Issue 12, pp. 1194-200, (2011) (PubMed).

  • Target

    MLXIPL (MLX Interacting Protein-Like (MLXIPL))

    Andere Bezeichnung

    MLXIPL

    Hintergrund

    This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23.



    Molekulargewicht

    93.1 kDa

    UniProt

    Q9NP71

    Pathways

    Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
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