MLXIPL Antikörper (AA 18-143)
Kurzübersicht für MLXIPL Antikörper (AA 18-143) (ABIN1724913)
Target
Alle MLXIPL Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 18-143
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Verwendungszweck
- MLXIPL Antibody
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Aufreinigung
- Ascitic fluid
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Immunogen
- Purified recombinant fragment of human MLXIPL (AA: 18-143) expressed in E. Coli.
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Isotyp
- IgG1
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Applikationshinweise
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ELISA: 1/10000
ICC: 1/200 - 1/1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Ascitic fluid containing 0.03 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Glucose-induced nuclear shuttling of ChREBP is mediated by sorcin and Ca(2+) ions in pancreatic β-cells." in: Diabetes, Vol. 61, Issue 3, pp. 574-85, (2012) (PubMed).
: "ChREBP expression in the liver, adipose tissue and differentiated preadipocytes in human obesity." in: Biochimica et biophysica acta, Vol. 1811, Issue 12, pp. 1194-200, (2011) (PubMed).
: "
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Glucose-induced nuclear shuttling of ChREBP is mediated by sorcin and Ca(2+) ions in pancreatic β-cells." in: Diabetes, Vol. 61, Issue 3, pp. 574-85, (2012) (PubMed).
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- MLXIPL (MLX Interacting Protein-Like (MLXIPL))
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Andere Bezeichnung
- MLXIPL
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Hintergrund
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This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23.
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Molekulargewicht
- 93.1 kDa
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UniProt
- Q9NP71
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Pathways
- Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
Target
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