MCAM Antikörper (AA 84-189)
(2 Referenzen)Kurzübersicht für MCAM Antikörper (AA 84-189) (ABIN1724898)
Target
Alle MCAM Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 84-189
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Verwendungszweck
- MCAM Antibody
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Aufreinigung
- Purified antibody
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Immunogen
- Purified recombinant fragment of human MCAM (AA: 84-189) expressed in E. Coli.
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Isotyp
- IgG1
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anti-Melanoma Cell Adhesion Molecule (MCAM) (AA 84-189) antibody
MCAM Reaktivität: Human FACS, IHC, WB, ELISA Wirt: Maus Monoclonal 6C3E6 unconjugated
anti-Melanoma Cell Adhesion Molecule (MCAM) (AA 50-646) antibodyMCAM Reaktivität: Human FACS, WB, IF, ELISA Wirt: Maus Monoclonal 4D10C7 unconjugated
anti-Melanoma Cell Adhesion Molecule (MCAM) (AA 447-646) antibodyMCAM Reaktivität: Human IHC, WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Melanoma Cell Adhesion Molecule (MCAM) antibodyMCAM Reaktivität: Human FACS, IHC, WB, IF, ELISA Wirt: Kaninchen Monoclonal 8A10 unconjugated Recombinant Antibody
anti-Melanoma Cell Adhesion Molecule (MCAM) antibodyMCAM Reaktivität: Human, Maus, Ratte IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Melanoma Cell Adhesion Molecule (MCAM) (AA 1-646) antibodyMCAM Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated
anti-Melanoma Cell Adhesion Molecule (MCAM) (AA 226-374) antibodyMCAM Reaktivität: Human IHC, StM Wirt: Maus Monoclonal MCAM-3046 unconjugated
anti-Melanoma Cell Adhesion Molecule (MCAM) antibodyMCAM Reaktivität: Human, Maus, Ratte IHC, WB Wirt: Kaninchen Polyclonal unconjugated
anti-Melanoma Cell Adhesion Molecule (MCAM) antibodyMCAM Reaktivität: Human, Maus, Kaninchen, Hund FACS, WB, IP, IHC (p), ICC, IHC (fro) Wirt: Maus Monoclonal P1H12 unconjugated
anti-Melanoma Cell Adhesion Molecule (MCAM) (AA 201-300) antibodyMCAM Reaktivität: Human, Ratte FACS, WB, ELISA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- ELISA: 1/10000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "CD146, a multi-functional molecule beyond adhesion." in: Cancer letters, Vol. 330, Issue 2, pp. 150-62, (2013) (PubMed).
: "The involvement of CD146 and its novel ligand Galectin-1 in apoptotic regulation of endothelial cells." in: The Journal of biological chemistry, Vol. 288, Issue 4, pp. 2571-9, (2013) (PubMed).
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: "CD146, a multi-functional molecule beyond adhesion." in: Cancer letters, Vol. 330, Issue 2, pp. 150-62, (2013) (PubMed).
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- MCAM (Melanoma Cell Adhesion Molecule (MCAM))
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Andere Bezeichnung
- MCAM
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Hintergrund
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The protein encoded by this gene plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during
embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration
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Molekulargewicht
- 71.6 kDa
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Gen-ID
- 4162
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UniProt
- P43121
Target
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