Dieser Anti-PAPLN Antikörper ist ein Maus Monoklonal Antikörper zur Detektion von PAPLN in ELISA. Geeignet für Human. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.
Purified antibody in PBS with 0.05 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Fessler, Kramerova, Kramerov, Chen, Fessler: "Papilin, a novel component of basement membranes, in relation to ADAMTS metalloproteases and ECM development." in: The international journal of biochemistry & cell biology, Vol. 36, Issue 6, pp. 1079-84, (2004) (PubMed).
Kramerova, Kawaguchi, Fessler, Nelson, Chen, Kramerov, Kusche-Gullberg, Kramer, Ackley, Sieron, Prockop, Fessler: "Papilin in development; a pericellular protein with a homology to the ADAMTS metalloproteinases." in: Development (Cambridge, England), Vol. 127, Issue 24, pp. 5475-85, (2001) (PubMed).
Papilin is an extracellular matrix glycoprotein involved in, thin matrix layers during gastrulation, matrix associated with wandering, phagocytic hemocytes, basement membranes and space-filling matrix during Drosophila development.Determination of its cDNA sequence led to the identification of Caenorhabditis and mammalian papilins. A distinctly conserved 'papilin cassette' of domains at the amino-end of papilins is also the carboxyl-end of the ADAMTS subgroup of secreted, matrix-associated metalloproteinases, this cassette contains one thrombospondin type 1 (TSR) domain, a specific cysteine-rich domain and several partial TSR domains. In vitro, papilin non-competitively inhibits procollagen N-proteinase, an ADAMTS metalloproteinase.