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CA9 Antikörper (AA 37-186)

Dieses Anti-CA9-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von CA9 in WB, IHC und ELISA. Geeignet für Human. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.
Produktnummer ABIN1724883

Kurzübersicht für CA9 Antikörper (AA 37-186) (ABIN1724883)

Target

Alle CA9 Antikörper anzeigen
CA9 (Carbonic Anhydrase IX (CA9))

Reaktivität

  • 109
  • 30
  • 27
  • 23
  • 5
  • 4
  • 4
  • 2
Human

Wirt

  • 95
  • 40
Maus

Klonalität

  • 69
  • 66
Monoklonal

Konjugat

  • 66
  • 13
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CA9 Antikörper ist unkonjugiert

Applikation

  • 86
  • 56
  • 32
  • 32
  • 26
  • 19
  • 17
  • 14
  • 13
  • 13
  • 11
  • 10
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Klon

7C4A5
  • Bindungsspezifität

    • 15
    • 9
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 37-186

    Verwendungszweck

    CA9 Antibody

    Aufreinigung

    Purified antibody

    Immunogen

    Purified recombinant fragment of human CA9 (AA: 37-186) expressed in E. Coli.

    Isotyp

    IgG1
  • Applikationshinweise

    ELISA: 1/10000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified antibody in PBS with 0.05 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Neumeister, Sullivan, Lindner, Lezon-Geyda, Li, Zavada, Martel, Glazer, Tuck, Rimm, Harris: "Hypoxia-induced protein CAIX is associated with somatic loss of BRCA1 protein and pathway activity in triple negative breast cancer." in: Breast cancer research and treatment, Vol. 136, Issue 1, pp. 67-75, (2012) (PubMed).

    Pinheiro, Sousa, Albergaria, Paredes, Dufloth, Vieira, Schmitt, Baltazar: "GLUT1 and CAIX expression profiles in breast cancer correlate with adverse prognostic factors and MCT1 overexpression." in: Histology and histopathology, Vol. 26, Issue 10, pp. 1279-86, (2011) (PubMed).

  • Target

    CA9 (Carbonic Anhydrase IX (CA9))

    Andere Bezeichnung

    CA9

    Hintergrund

    Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12.

    Molekulargewicht

    49.7 kDa

    Gen-ID

    768

    UniProt

    Q16790
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