Dynamin 1-Like Antikörper (AA 69-213)
Kurzübersicht für Dynamin 1-Like Antikörper (AA 69-213) (ABIN1724863)
Target
Alle Dynamin 1-Like (DNM1L) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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                                            Bindungsspezifität
- AA 69-213
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                                            Verwendungszweck
- DNM1L Antibody
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                                            Aufreinigung
- Purified antibody
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                                            Immunogen
- Purified recombinant fragment of human DNM1L (AA: 69-213) expressed in E. Coli.
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                                            Isotyp
- IgG1
 
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                                            Applikationshinweise
- ELISA: 1/10000
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                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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                                            Format
- Liquid
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                                            Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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                                            Konservierungsmittel
- Sodium azide
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                                            Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            Lagerung
- 4 °C,-20 °C
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                                            Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
 
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    - 
                                            : "Defects in mitochondrial fission protein dynamin-related protein 1 are linked to apoptotic resistance and autophagy in a lung cancer model."    in: PLoS ONE, Vol. 7, Issue 9, pp. e45319, (2012)         (PubMed).        
 : "Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension." in: Circulation research, Vol. 110, Issue 11, pp. 1484-97, (2012) (PubMed).
 
 
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                                            : "Defects in mitochondrial fission protein dynamin-related protein 1 are linked to apoptotic resistance and autophagy in a lung cancer model."    in: PLoS ONE, Vol. 7, Issue 9, pp. e45319, (2012)         (PubMed).        
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    - Dynamin 1-Like (DNM1L)
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                                            Andere Bezeichnung
- DNM1L
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                                            Hintergrund
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                        The protein encoded by this gene is a member of the dynamin superfamily of GTPases. Members of the dynamin-related subfamily, including the S. cerevisiae proteins Dnm1 and Vps1, contain the N-terminal tripartite GTPase domain but do not have the pleckstrin homology or proline-rich domains. This protein establishes mitochondrial morphology through a role in distributing mitochondrial tubules throughout the cytoplasm. The gene has 3 alternatively spliced transcripts encoding different isoforms. These transcripts are alternatively polyadenylated. 
 
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                                            Molekulargewicht
- 81.9 kDa
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                                            UniProt
- O00429
 Target
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