Paired Box 3 Antikörper (AA 142-203)
Kurzübersicht für Paired Box 3 Antikörper (AA 142-203) (ABIN1724816)
Target
Alle Paired Box 3 (PAX3) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 142-203
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Verwendungszweck
- PAX3 Antibody
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Aufreinigung
- Ascitic fluid
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Immunogen
- Purified recombinant fragment of human PAX3 (AA: 142-203) expressed in E. Coli.
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Isotyp
- IgG1
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Applikationshinweise
- ELISA: 1/10000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Ascitic fluid containing 0.03 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "FGF2 regulates melanocytes viability through the STAT3-transactivated PAX3 transcription." in: Cell death and differentiation, Vol. 19, Issue 4, pp. 616-22, (2012) (PubMed).
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: "FGF2 regulates melanocytes viability through the STAT3-transactivated PAX3 transcription." in: Cell death and differentiation, Vol. 19, Issue 4, pp. 616-22, (2012) (PubMed).
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- Paired Box 3 (PAX3)
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Andere Bezeichnung
- PAX3
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Hintergrund
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This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2,13)(q35,q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.
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Molekulargewicht
- 53 kDa
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UniProt
- P23760
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Pathways
- Sensory Perception of Sound, Tube Formation
Target
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