Dynactin 4 Antikörper (AA 57-298)
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- Target Alle Dynactin 4 (DCTN4) Antikörper anzeigen
- Dynactin 4 (DCTN4)
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Bindungsspezifität
- AA 57-298
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Dynactin 4 Antikörper ist unkonjugiert
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Applikation
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
- Aufreinigung
- purified
- Immunogen
- Purified recombinant fragment of human DCTN4 (AA: 57-298) expressed in E. coli.
- Klon
- 3G9D7
- Isotyp
- IgG1
- Top Product
- Discover our top product DCTN4 Primärantikörper
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- Applikationshinweise
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- 4°C, -20°C for long term storage
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An ankyrin-based mechanism for functional organization of dystrophin and dystroglycan." in: Cell, Vol. 135, Issue 7, pp. 1189-200, (2008) (PubMed).
: "Copper-dependent interaction of dynactin subunit p62 with the N terminus of ATP7B but not ATP7A." in: The Journal of biological chemistry, Vol. 281, Issue 20, pp. 14006-14, (2006) (PubMed).
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An ankyrin-based mechanism for functional organization of dystrophin and dystroglycan." in: Cell, Vol. 135, Issue 7, pp. 1189-200, (2008) (PubMed).
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- Target
- Dynactin 4 (DCTN4)
- Andere Bezeichnung
- DCTN4 (DCTN4 Produkte)
- Hintergrund
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Description: Dynactin 4 could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton.The dynactin complex binds cargo, such as vesicles and organelles, to cytoplasmic dynein for retrograde microtubule-mediated trafficking and could feasibly be involved in the copper-regulated trafficking of ATP7B. , ,
Aliases: P62, DYN4
- Molekulargewicht
- 52.3 kDa
- Gen-ID
- 51164
- HGNC
- 51164
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