Dynactin 4 Antikörper (AA 57-298)
Kurzübersicht für Dynactin 4 Antikörper (AA 57-298) (ABIN1724791)
Target
Alle Dynactin 4 (DCTN4) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 57-298
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Verwendungszweck
- DCTN4 Antibody
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Aufreinigung
- Ascitic fluid
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Immunogen
- Purified recombinant fragment of human DCTN4 (AA: 57-298) expressed in E. Coli.
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Isotyp
- IgG1
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Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Ascitic fluid containing 0.03 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "An ankyrin-based mechanism for functional organization of dystrophin and dystroglycan." in: Cell, Vol. 135, Issue 7, pp. 1189-200, (2008) (PubMed).
: "Copper-dependent interaction of dynactin subunit p62 with the N terminus of ATP7B but not ATP7A." in: The Journal of biological chemistry, Vol. 281, Issue 20, pp. 14006-14, (2006) (PubMed).
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: "An ankyrin-based mechanism for functional organization of dystrophin and dystroglycan." in: Cell, Vol. 135, Issue 7, pp. 1189-200, (2008) (PubMed).
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- Dynactin 4 (DCTN4)
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Andere Bezeichnung
- DCTN4
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Hintergrund
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Dynactin 4 could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton.The dynactin complex binds cargo, such as vesicles and organelles, to cytoplasmic dynein for retrograde microtubule-mediated trafficking and could feasibly be involved in the copper-regulated trafficking of ATP7B.
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Molekulargewicht
- 52.3 kDa
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Gen-ID
- 51164
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UniProt
- Q9UJW0
Target
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