Cytokeratin 5 Antikörper (AA 316-590)

Produktnummer ABIN1724789

Der Maus Monoklonal Anti-Cytokeratin 5-Antikörper wurde für WB, IHC, ELISA und FACS validiert. Er ist geeignet, Cytokeratin 5 in Proben von Human zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für Cytokeratin 5 Antikörper (AA 316-590) (ABIN1724789)

Target: Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Cytokeratin 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Klon: 10C11E6

Produktdetails anti-Cytokeratin 5 Antikörper

Bindungsspezifität: AA 316-590

Verwendungszweck: CK5 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human CK5 (AA: 316-590) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-Cytokeratin 5 Antikörper (ABIN1724789)

Grin, OMalley, Mulligan: "Cytokeratin 5 and estrogen receptor immunohistochemistry as a useful adjunct in identifying atypical papillary lesions on breast needle core biopsy." in: The American journal of surgical pathology, Vol. 33, Issue 11, pp. 1615-23, (2009) (PubMed).

Sugiyama-Fukamatsu, Suzuki, Nakanishi, Iwatsuki: "Epidermolysis bullosa nevus arising in a patient with Dowling-Meara type epidermolysis bullosa simplex with a novel K5 mutation." in: The Journal of dermatology, Vol. 36, Issue 8, pp. 447-52, (2009) (PubMed).

Details zu Cytokeratin 5

Target: Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))

Andere Bezeichnung: CK5

Hintergrund: The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

Molekulargewicht: 62.4 kDa

Gen-ID: 3852

UniProt: P13647