GUCY1A1 Antikörper (AA 22-214)

Produktnummer ABIN1724787

Dieses Anti-GUCY1A1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von GUCY1A1 in WB, ELISA, IHC, FACS und ICC. Geeignet für Human. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Kurzübersicht für GUCY1A1 Antikörper (AA 22-214) (ABIN1724787)

Target: GUCY1A1 (Guanylate Cyclase 1 Soluble Subunit Alpha (GUCY1A1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GUCY1A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Klon: 3G6B2

Produktdetails anti-GUCY1A1 Antikörper

Bindungsspezifität: AA 22-214

Verwendungszweck: GUCY1A3 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human GUCY1A3 (AA: 22-214) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-GUCY1A1 Antikörper (ABIN1724787)

Cai, Hsieh, Gao, Kannan, Bhansali, Govardhan, Dutta, Shemshedini: "Soluble guanylyl cyclase ?1 and p53 cytoplasmic sequestration and down-regulation in prostate cancer." in: Molecular endocrinology (Baltimore, Md.), Vol. 26, Issue 2, pp. 292-307, (2012) (PubMed).

Zhong, Pan, Liu, Wang, Ying, Su, Huang, Tan: "A novel insight into the heme and NO/CO binding mechanism of the alpha subunit of human soluble guanylate cyclase." in: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, Vol. 16, Issue 8, pp. 1227-39, (2011) (PubMed).

Details zu GUCY1A1

Target: GUCY1A1 (Guanylate Cyclase 1 Soluble Subunit Alpha (GUCY1A1))

Andere Bezeichnung: GUCY1A3

Hintergrund: Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene.

Molekulargewicht: 77.5 kDa

Gen-ID: 2982

Pathways: Myometrial Relaxation and Contraction