Fc epsilon RI/FCER1A Antikörper (AA 42-103)
Kurzübersicht für Fc epsilon RI/FCER1A Antikörper (AA 42-103) (ABIN1724785)
Target
Alle Fc epsilon RI/FCER1A (FCER1A) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 42-103
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Verwendungszweck
- FCER1A Antibody
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Aufreinigung
- Ascitic fluid
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Immunogen
- Purified recombinant fragment of human FCER1A (AA:42-103) expressed in E. Coli.
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Isotyp
- IgG1
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Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Ascitic fluid containing 0.03 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Association of polymorphisms in the promoter region of FCER1A gene with atopic dermatitis, chronic uticaria, asthma, and serum immunoglobulin E levels in a Han Chinese population." in: Human immunology, Vol. 73, Issue 3, pp. 301-5, (2012) (PubMed).
: "Naturally occurring FCER1A N222K mutation - its ethnicity-dependent distribution and a role in atopic dermatitis." in: Molecular immunology, Vol. 48, Issue 8, pp. 979-80, (2011) (PubMed).
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: "Association of polymorphisms in the promoter region of FCER1A gene with atopic dermatitis, chronic uticaria, asthma, and serum immunoglobulin E levels in a Han Chinese population." in: Human immunology, Vol. 73, Issue 3, pp. 301-5, (2012) (PubMed).
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- Fc epsilon RI/FCER1A (FCER1A) (Fc Fragment of IgE Receptor Ia (FCER1A))
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Andere Bezeichnung
- FCER1A
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Hintergrund
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The immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine that are responsible for allergy symptoms are released. This receptor is comprised of an alpha subunit, a beta subunit, and two gamma subunits. The protein encoded by this gene represents the alpha subunit.
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Molekulargewicht
- 29.6 kDa
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Pathways
- Fc-epsilon Rezeptor Signalübertragung, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Target
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