IGFBP2 Antikörper (AA 180-328)

Produktnummer ABIN1724698

Dieser Maus Monoklonal Antikörper detektiert spezifisch IGFBP2 in IHC und ELISA. Es zeigt Reaktivität gegenüber Proben von Human. Es wurde in 2+ Publikationen zitiert.

Kurzübersicht für IGFBP2 Antikörper (AA 180-328) (ABIN1724698)

Target: IGFBP2 (Insulin-Like Growth Factor Binding Protein 2, 36kDa (IGFBP2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IGFBP2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Klon: 1F6F6

Produktdetails anti-IGFBP2 Antikörper

Bindungsspezifität: AA 180-328

Verwendungszweck: IGFBP2 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of protein IGFBP2 (aa180-328) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-IGFBP2 Antikörper (ABIN1724698)

Miyake, Hara, Yamanaka, Muramaki, Gleave, Eto: "Introduction of insulin-like growth factor binding protein-2 gene into human bladder cancer cells enhances their metastatic potential." in: Oncology reports, Vol. 13, Issue 2, pp. 341-5, (2005) (PubMed).

Fisher, Meyer, Garber, Dealy: "Role of IGFBP2, IGF-I and IGF-II in regulating long bone growth." in: Bone, Vol. 37, Issue 6, pp. 741-50, (2005) (PubMed).

Details zu IGFBP2

Target: IGFBP2 (Insulin-Like Growth Factor Binding Protein 2, 36kDa (IGFBP2))

Andere Bezeichnung: IGFBP2

Hintergrund: IGFBP2: insulin-like growth factor binding protein 2. IGFBP2 is a member of the ISGBP family which bind various IGFs. IGFBP2 is overexpressed in a wide spectrum of other cancers, including glioma, prostate cancer, synovial sarcoma, neuroblastoma, colon cancer, adrenocortical cancer, lung cancer, Wilms' tumor, and hepatoblastoma. The overexpression of IGFBP2 also correlates with the aggressiveness of some tumors. IGFBP2 activates the expression of matrix metalloprotease 2, which contributes to cell invasiveness.

Gen-ID: 3485

UniProt: P18065

Pathways: Myometrial Relaxation and Contraction, Growth Factor Binding, Activated T Cell Proliferation