YES1 Antikörper (AA 10-193)

Produktnummer ABIN1724691

Produktdetails anti-YES1 Antikörper

Target: YES1 (V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 (YES1))

Bindungsspezifität: AA 10-193

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser YES1 Antikörper ist unkonjugiert

Applikation: ELISA

Verwendungszweck: YES1 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of YES (aa10-193) expressed in E. Coli.

Klon: 2F3E6

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-YES1 Antikörper (ABIN1724691)

Rush, Moritz, Lee, Guo, Goss, Spek, Zhang, Zha, Polakiewicz, Comb: "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells." in: Nature biotechnology, Vol. 23, Issue 1, pp. 94-101, (2005) (PubMed).

Reinehr, Becker, Höngen, Haüssinger: "The Src family kinase Yes triggers hyperosmotic activation of the epidermal growth factor receptor and CD95." in: The Journal of biological chemistry, Vol. 279, Issue 23, pp. 23977-87, (2004) (PubMed).

Annerén, Cowan, Melton: "The Src family of tyrosine kinases is important for embryonic stem cell self-renewal." in: The Journal of biological chemistry, Vol. 279, Issue 30, pp. 31590-8, (2004) (PubMed).

Details zu YES1

Target: YES1 (V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 (YES1))

Andere Bezeichnung: YES1 (YES1 Produkte)

Hintergrund: YES1, v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1. This gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. This gene lies in close proximity to thymidylate synthase gene on chromosome 18, and a corresponding pseudogene has been found on chromosome 22.

Gen-ID: 7525

UniProt: P07947

Pathways: CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling