EhpB1 (AA 19-133) Antikörper

Produktnummer ABIN1724690

Produktdetails

Target: EhpB1

Bindungsspezifität: AA 19-133

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Applikation: Immunohistochemistry (IHC), ELISA, Western Blotting (WB)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of EphB1 (aa19-133) expressed in E. coli.

Klon: 5F10A4

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen

Huynh-Do, Vindis, Liu, Cerretti, McGrew, Enriquez, Chen, Daniel: "Ephrin-B1 transduces signals to activate integrin-mediated migration, attachment and angiogenesis." in: Journal of cell science, Vol. 115, Issue Pt 15, pp. 3073-81, (2002) (PubMed).

Prevost, Woulfe, Tanaka, Brass: "Interactions between Eph kinases and ephrins provide a mechanism to support platelet aggregation once cell-to-cell contact has occurred." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 14, pp. 9219-24, (2002) (PubMed).

Antigendetails

Target: EhpB1

Hintergrund:

Description: EhpB1: EPH receptor B1. It is a receptor for ephrin-B family members. Ephrin receptors and their ligands, the ephrins, medate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family.

Aliases: ELK, NET, Hek6, EPHT2, EPHB1

Molekulargewicht: 110 kDa

Gen-ID: 2047

HGNC: 2047