EhpB1 (AA 19-133) Antikörper

Produktnummer ABIN1724690

Der Maus Monoklonal Anti--Antikörper wurde für IHC, ELISA und WB validiert. Er ist geeignet, in Proben von Human zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für EhpB1 (AA 19-133) Antikörper (ABIN1724690)

Target: EhpB1

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Applikation: Immunohistochemistry (IHC), ELISA, Western Blotting (WB)

Klon: 5F10A4

Produktdetails

Bindungsspezifität: AA 19-133

Verwendungszweck: EhpB1 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of EphB1 (aa19-133) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen

Huynh-Do, Vindis, Liu, Cerretti, McGrew, Enriquez, Chen, Daniel: "Ephrin-B1 transduces signals to activate integrin-mediated migration, attachment and angiogenesis." in: Journal of cell science, Vol. 115, Issue Pt 15, pp. 3073-81, (2002) (PubMed).

Prevost, Woulfe, Tanaka, Brass: "Interactions between Eph kinases and ephrins provide a mechanism to support platelet aggregation once cell-to-cell contact has occurred." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 14, pp. 9219-24, (2002) (PubMed).

Antigendetails

Target: EhpB1

Hintergrund: EhpB1: EPH receptor B1. It is a receptor for ephrin-B family members. Ephrin receptors and their ligands, the ephrins, medate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family.

Molekulargewicht: 110 kDa

UniProt: P54762