BNP Antikörper

Produktnummer ABIN1724676

Dieses Anti-BNP-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von BNP in IHC und ELISA. Geeignet für Human. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Kurzübersicht für BNP Antikörper (ABIN1724676)

Target: BNP (Brain Natriuretic Peptide (BNP))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser BNP Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Klon: 9H6B4

Produktdetails anti-BNP Antikörper

Verwendungszweck: BNP Antibody

Sequenz: Gly-Leu-Gln-Glu-Gln-Arg-Asn-His-Leu-Gln-Gly-Lys-Leu-Cys

Aufreinigung: Ascitic fluid

Immunogen: Synthetic peptide corresponding to aa (Gly-Leu-Gln-Glu-Gln-Arg-Asn-His-Leu-Gln-Gly-Lys-Leu-Cys) of human BNP, conjugated to KLH.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-BNP Antikörper (ABIN1724676)

Pfister, Erdmann, Schneider: "[Natriuretic peptides BNP and NT-pro-BNP--the "new troponins" for estimation of heart failure?]." in: Deutsche medizinische Wochenschrift (1946), Vol. 128, Issue 18, pp. 1007-12, (2003) (PubMed).

Dawson, Struthers: "Screening for treatable left ventricular abnormalities in diabetic patients." in: Expert opinion on biological therapy, Vol. 3, Issue 1, pp. 107-12, (2003) (PubMed).

Details zu BNP

Target: BNP (Brain Natriuretic Peptide (BNP))

Andere Bezeichnung: BNP

Hintergrund: BNP (brain natriuretic peptide) belongs to a family of structurally similar peptide hormones, which includes atrial natriuretic peptide (ANP), BNP, C-type natriuretic peptide (CNP) and urodilatin. ANP and BNP act mainly as cardiac hormones, produced primarily by the atrium and ventricle, respectively, while the gene encoding C-type natriuretic peptide is expressed mainly in the brain. BNP circulates in blood as a peptide hormone with natriuretic, vasodilatory and renin inhibitory properties. It is secreted predominantly by the left ventricular myocytes in response to volume expansion and pressure overload. These peptides are characterized by a common 17 amino acid ring structure with a disulfide bond between two cystein residues. This ring structure shows high homology between different natriuretic.

Gen-ID: 4879

UniProt: P16860

Pathways: Hormone Activity