Apolipoprotein M Antikörper

Produktnummer ABIN1724662

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Apolipoprotein M in ELISA und ICC. Er zeigt eine Reaktivität gegenüber Human und wurde in 3+ Publikationen erwähnt.

Kurzübersicht für Apolipoprotein M Antikörper (ABIN1724662)

Target: Apolipoprotein M (APOM)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Apolipoprotein M Antikörper ist unkonjugiert

Applikation: ELISA, Immunocytochemistry (ICC)

Klon: 10C3G5

Produktdetails anti-Apolipoprotein M Antikörper

Verwendungszweck: ApoM Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of ApoM expressed in E. Coli.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-Apolipoprotein M Antikörper (ABIN1724662)

Wolfrum, Poy, Stoffel: "Apolipoprotein M is required for prebeta-HDL formation and cholesterol efflux to HDL and protects against atherosclerosis." in: Nature medicine, Vol. 11, Issue 4, pp. 418-22, (2005) (PubMed).

Xu, Nilsson-Ehle, Ahrén: "Correlation of apolipoprotein M with leptin and cholesterol in normal and obese subjects." in: The Journal of nutritional biochemistry, Vol. 15, Issue 10, pp. 579-82, (2004) (PubMed).

Zhang, Jiao, Hurtig, Dong, Zheng, Luo, Nilsson-Ehle, Ye, Xu: "Expression pattern of apolipoprotein M during mouse and human embryogenesis." in: Acta histochemica, Vol. 106, Issue 2, pp. 123-8, (2004) (PubMed).

Details zu Apolipoprotein M

Target: Apolipoprotein M (APOM)

Andere Bezeichnung: ApoM

Hintergrund: ApoM (apolipoprotein M, also designated G3a or NG20), with 188-amino acid protein(about 21 kDa), is an apolipoprotein and member of the lipocalin protein family. The Apo-proteins are involved in the specific binding of cellular receptors, the regulation of lipolytic enzymes, and the process of lipid exchange. The encoded protein is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. The N-terminal region of Apo-M contains hydrophobic residues that may promote association with the phospholipid layer of lipoprotein particles. In vitro, Apo-M is glycosylated when translated in the presence of microsomes, and remains associated with the microsomes after carbonate treatment. Apo-M is expressed in liver and kidney, and is secreted into the bloodstream in HDLs, and also found in triglyceride-rich lipoproteins and LDLs.

Molekulargewicht: 21 kDa

Gen-ID: 55937

UniProt: O95445