Estrogen Receptor alpha Antikörper (AA 410-592)
Kurzübersicht für Estrogen Receptor alpha Antikörper (AA 410-592) (ABIN1724648)
Target
Alle Estrogen Receptor alpha (ESR1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 410-592
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Verwendungszweck
- ER-alpha Antibody
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Aufreinigung
- Purified antibody
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Immunogen
- Purified recombinant fragment of human ER-alpha (410-592aa) expressed in E. Coli.
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Isotyp
- IgG1
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anti-Estrogen Receptor 1 (ESR1) antibody
ESR1 Reaktivität: Human WB, IHC Wirt: Maus Monoclonal ESR1-1904 unconjugated
anti-Estrogen Receptor 1 (ESR1) (AA 129-312) antibodyESR1 Reaktivität: Human WB, IHC, IF, FACS Wirt: Maus Monoclonal ESR1-3557 unconjugated
anti-Estrogen Receptor 1 (ESR1) (AA 246-273) antibodyESR1 Reaktivität: Human, Maus WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB33807 unconjugated
anti-Estrogen Receptor 1 (ESR1) (AA 2-185) antibodyESR1 Reaktivität: Human, Ratte WB, IHC, ELISA, FACS, ICC Wirt: Maus Monoclonal 6A6E8 unconjugated
anti-Estrogen Receptor 1 (ESR1) (C-Term) antibodyESR1 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Estrogen Receptor 1 (ESR1) (AA 2-185) antibodyESR1 Reaktivität: Human WB, IHC, IF, FACS Wirt: Maus Monoclonal ER506 unconjugated
anti-Estrogen Receptor 1 (ESR1) antibodyESR1 Reaktivität: Human WB, IHC, FACS, ICC, IP Wirt: Maus Monoclonal 119-13 unconjugated
anti-Estrogen Receptor 1 (ESR1) (pSer167) antibodyESR1 Reaktivität: Human, Ratte ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Estrogen Receptor 1 (ESR1) (AA 246-273) antibodyESR1 Reaktivität: Human WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Estrogen Receptor 1 (ESR1) (AA 233-483) antibodyESR1 Reaktivität: Maus WB, IHC, ICC, IP Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- ELISA: 1/10000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified antibody in PBS containing 0.03 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
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Andere Bezeichnung
- ER-alpha
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Hintergrund
- The estrogen receptor (ER) is a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. Alternative splicing results in several ER mRNA transcripts, which differ primarily in their 5-prime untranslated regions. Two isoforms of the human ER, ERA and ER-beta, occur, each with distinct tissue and cell patterns of expression. Pelletier and El-Alfy (2000) studied the immunocytochemical localization of ESRA and ESRB in human reproductive tissues. In the ovary, ERB immunoreactivity was found in nuclei of granulosa cells of growing follicles at all stages from primary to mature follicles, interstitial gland, and germinal epithelium cells. Nuclear staining for ERA occurred in thecal, interstitial gland, and germinal epithelium cells. In the uterus, strong ERA immunoreactivity was detected in nuclei of epithelial, stromal, and muscle cells.
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UniProt
- P03372
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Pathways
- Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
Target
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