Tacrolimus (FK506) Antikörper

Produktnummer ABIN1722861

Der Maus Monoklonal anti-Tacrolimus Antikörper (Klon FK1) (ABIN1722861) detektiert spezifisch Tacrolimus in ELISA und WB. Dieser Antikörper reagiert spezifisch mit Proben aus Chemical.

Kurzübersicht für Tacrolimus (FK506) Antikörper (ABIN1722861)

Target: Tacrolimus (FK506)

Reaktivität: Chemical

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Klon: FK1

Produktdetails

Spezifität: Reacts with conjugated and non-conjugated FK-506 (Kd=10E-9M)

Aufreinigung: Purified

Immunogen: FK-506 conjugated to bovine serum albumin.

Isotyp: IgM

Anwendungsinformationen

Applikationshinweise: Working dilution: Optimal dilution should be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Dilute in PBS or medium which is identical to that used in the assay system.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: Tacrolimus (FK506)

Andere Bezeichnung: FK-506

Substanzklasse: Chemical

Hintergrund: FK-506 is a novel macrolide with similar, but more potent, immunosuppressant activity than cyclosporine. FK-506 is used for primary or rescue immunosuppression in patients after solid organ transplantation. Clinically relevant side effects of FK-506 administration are nephrotoxicity, neurotoxicity, diabetes mellitus, and hypertension. Most of these side effects are related to blood levels of FK-506 rather than dosage. Therefore, therapeutic drug monitoring of FK-506 is a prerequisite for therapy. The whole blood target level range aimed for in clinical practice is 3.0-20.0 ng/mL and depends on the patient's liver function, the nature of organ transplantation, and the time after transplantation.

Tacrolimus Fujimycin CAS : 109581-93-3 C44H69NO12 . H2O