Hsc70 Antikörper

Produktnummer ABIN1721551

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Hsc70 in WB, IHC, ELISA und IP. Er zeigt eine Reaktivität gegenüber Human, Ratte und Maus.

Kurzübersicht für Hsc70 Antikörper (ABIN1721551)

Target: Hsc70 (HSPA8) (Heat Shock 70kDa Protein 8 (HSPA8))

Reaktivität: Human, Ratte, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Hsc70 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Klon: 1F2-H5

Produktdetails anti-Hsc70 Antikörper

Spezifität: Reacts with human Hsc70 (Hsp73). Cross-reacts with mouse and rat protein.

Aufreinigung: Purified (protein G)

Immunogen: Human Hsc70

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
WB1 μg/mL ELISA1-10 μg/mL IHC1-10 μg/mL IP1-10 μg/mL

Positive control: HeLa cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, pH 7.4

Handhabung: Dilute in PBS or medium which is identical to that used in the assay system.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Short term storage at+4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 months from date of receipt.

Haltbarkeit: 6 months

Details zu Hsc70

Target: Hsc70 (HSPA8) (Heat Shock 70kDa Protein 8 (HSPA8))

Andere Bezeichnung: Hsc70 (Hsp73)

Hintergrund: Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes.

Heat shock cognate 71 kDa protein Heat shock 70 kDa protein 8 Lipopolysaccharide-associated protein 1, LAP-1, LPS-associated protein 1 Gene name: HSPA8, HSC70, HSP73, HSPA10

Gen-ID: 3312

UniProt: P11142