TXNDC5 Antikörper (AA 52-63)

Produktnummer ABIN1721515

Dieser Maus Monoklonal Antikörper erkennt spezifisch TXNDC5 in WB, ELISA, IHC, IF, IP und ICC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für TXNDC5 Antikörper (AA 52-63) (ABIN1721515)

Target: TXNDC5 (Thioredoxin Domain Containing 5 (Endoplasmic Reticulum) (TXNDC5))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TXNDC5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Klon: 2E7-7

Produktdetails anti-TXNDC5 Antikörper

Bindungsspezifität: AA 52-63

Spezifität: Reacts with human EndoPDI.

Aufreinigung: Purified (protein G)

Immunogen: Synthetic peptide corresponding to aa 52-63 (ADGEDGQDPHSK) of human EndoPDI (accession no. NP_001139021).

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
ICC(1:10 - 1:500) IF(1:10 - 1:500) IHC(1:10 - 1:500) IP(1:10 - 1:500) WB(1 μg/mL)

Positive control: Heat-shocked HeLa cell lysate.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Dilute in PBS or medium which is identical to that used in the assay system.

Lagerung: -20 °C

Informationen zur Lagerung: This antibody is stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.

Details zu TXNDC5

Target: TXNDC5 (Thioredoxin Domain Containing 5 (Endoplasmic Reticulum) (TXNDC5))

Andere Bezeichnung: EndoPDI

Hintergrund: Endothelial protein disulfide isomerase (EndoPDI) is a thiredoxin member of the protein disulfide isomerase family of chaperones. This enzyme is localized in the endoplasmic reticulum in primary endothelial cells but colocalizes with nucleoli in the nuclei of breast, colon, and kidney cancer cells. EndoPDI mRNA and protein expression is iduced by hypoxia and exhibits a protective effect on endothelial cells during hypoxia.

Thioredoxin domain containing 5 (endoplasmic reticulum) Endoplasmic reticulum resident protein 46, ER protein 46, ERp46 Thioredoxin-like protein p46 HCC2, HCC-2 STRF8 PDIA15 UNQ364 Gene name :TXNDC5

Gen-ID: 81567

UniProt: Q8NBS9

Pathways: Cell RedoxHomeostasis