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Hepcidin 25 Antikörper (AA 60-84)

HEPC25 Reaktivität: Maus, Ratte IF (p), IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1715141
  • Target Alle Hepcidin 25 (HEPC25) Antikörper anzeigen
    Hepcidin 25 (HEPC25)
    Bindungsspezifität
    • 29
    • 1
    • 1
    AA 60-84
    Reaktivität
    • 16
    • 15
    • 14
    Maus, Ratte
    Wirt
    • 31
    Kaninchen
    Klonalität
    • 31
    Polyklonal
    Konjugat
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser Hepcidin 25 Antikörper ist unkonjugiert
    Applikation
    • 25
    • 17
    • 13
    • 5
    • 5
    • 3
    • 1
    • 1
    Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from rat Hepcidin
    Isotyp
    IgG
  • Applikationshinweise
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    Hepcidin 25 (HEPC25)
    Andere Bezeichnung
    Hepcidin 25 (HEPC25 Produkte)
    Synonyme
    HEPC antikoerper, HFE2B antikoerper, LEAP1 antikoerper, PLTR antikoerper, hepcidin antimicrobial peptide antikoerper, HAMP antikoerper
    Hintergrund

    Synonyms: Hamp, HEPC, HEPC_RAT, HEPC_MOUSE, Hepc20, Hepc25, HEPCIDIN, Hepcidin, Hepcidin 20, Hepcidin 25, Hepcidin antimicrobial peptide, Hepcidin-20, Hepcidin25, HFE2, HFE2B, LEAP 1, LEAP-1, LEAP1, Liver expressed antimicrobial peptide, Liver-expressed antimicrobial peptide 1, PLTR, Putative liver tumor regressor.

    Background: The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure. [provided by RefSeq, Jul 2008].

    Gen-ID
    84604
    UniProt
    Q99MH3
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