ZFP36L1 Antikörper (pSer92)

Produktnummer ABIN1715062

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ZFP36L1 in ELISA, IF (cc), IF (p), IHC (p), IHC (fro) und ICC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für ZFP36L1 Antikörper (pSer92) (ABIN1715062)

Target: ZFP36L1 (ZFP36 Ring Finger Protein-Like 1 (ZFP36L1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZFP36L1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Produktdetails anti-ZFP36L1 Antikörper

Bindungsspezifität: pSer92

Homologie: Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human butyrate response factor 1 around the phosphorylation site of Ser92 [SF(p-S)EG]

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu ZFP36L1

Target: ZFP36L1 (ZFP36 Ring Finger Protein-Like 1 (ZFP36L1))

Andere Bezeichnung: ZFP36L1

Hintergrund:

Synonyms: butyrate response factor 1 phospho S92, Berg36, BRF1, butyrate response factor 1, C3H type like 1, cMG1, early response factor Berg36, EGF inducible protein CMG1, EGF response factor 1, ERF1, RNF162B, TIS11B, zinc finger protein.

Background: EGF response factor 1 is a zinc-binding protein encoded by the immediate-early response gene, Zfp-36. TIS11B, a relative of TTP, localizes to the nucleus and may function as a transcription factor involved in regulating the growth factor response. It is an evolutionarily conserved protein containing two C3H1-type zinc fingers and a repeating cys-his motif. TIS11B is an mRNA binding protein and is known to interact with the 3?-untranslated region of VEGF mRNA, thereby decreasing its stability. This suggests that TIS11B is a potential target in antiangiogenic therapy. In addition, TIS11B may also be an important regulator of myogenesis, as its expression is upregulated during murine myoblast differentiation.

Gen-ID: 677