VPREB1 Antikörper (AA 61-145)

Produktnummer ABIN1715058

Dieser Anti-VPREB1 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von VPREB1 in WB, ICC, ELISA, IF (cc), IF (p), IHC (fro) und IHC (p). Geeignet für Human.

Kurzübersicht für VPREB1 Antikörper (AA 61-145) (ABIN1715058)

Target: VPREB1 (Pre-B Lymphocyte 1 (VPREB1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VPREB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-VPREB1 Antikörper

Bindungsspezifität: AA 61-145

Homologie: Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human VPREB1/CD179a

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu VPREB1

Target: VPREB1 (Pre-B Lymphocyte 1 (VPREB1))

Andere Bezeichnung: VPREB1/CD179a

Hintergrund:

Synonyms: CD179 antigen like family member A, CD179 antigen-like family member A, CD179a, IGI, IGVPB, Immunoglobulin iota chain, Pre B lymphocyte 1, pre-B lymphocyte 1, Protein VPreB1, VpreB protein, VPREB 1, VPREB, VpreB protein, VPREB_HUMAN, VPREB1.

Background: VpreB is expressed in pre-B lymphocytes, but not in mature B cells or in other blood cell lineages. The gene which encodes VpreB maps to human chromosome 22q11.2. The VpreB and Lambda 5 genes encode the Iota and Omega polypeptide chains, respectively, which associate with the Ig-Mu chain to form a molecular complex that is expressed on the surface of pre-B cells. This complex presumably regulates Ig gene rearrangements in the early steps of B cell differentiation. In the mouse the two genes are simultaneously expressed in pre-B cells and belong to the same transcription unit. A primary transcript is synthesized from which the pre-B and Lambda 5 mRNAs are derived by alternative splicing. In the human, however, the two genes are separate and do not belong to the same transcription unit.

Gen-ID: 7441

Pathways: Production of Molecular Mediator of Immune Response, Regulation of Cell Size