GOT1L1 Antikörper (AA 201-300)

Produktnummer ABIN1715033

Der Kaninchen Polyklonal Anti-GOT1L1-Antikörper wurde für WB, IF (cc), IF (p), ELISA, IHC (p), ICC und IHC (fro) validiert. Er ist geeignet, GOT1L1 in Proben von Maus und Ratte zu detektieren.

Kurzübersicht für GOT1L1 Antikörper (AA 201-300) (ABIN1715033)

Target: GOT1L1 (Glutamic-Oxaloacetic Transaminase 1-Like 1 (GOT1L1))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GOT1L1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-GOT1L1 Antikörper

Bindungsspezifität: AA 201-300

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GOT1L1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu GOT1L1

Target: GOT1L1 (Glutamic-Oxaloacetic Transaminase 1-Like 1 (GOT1L1))

Andere Bezeichnung: GOT1L1

Hintergrund:

Synonyms: AATC2_HUMAN, cytoplasmic 2, Glutamate oxaloacetate transaminase 1-like protein 1, Glutamic oxaloacetic transaminase 1 like 1, GOT1L1, Putative aspartate aminotransferase, Putative aspartate aminotransferase, cytoplasmic 2, Transaminase A-like protein 1.

Background: GOT1L1, Glutamate oxaloacetate transaminase 1-like protein 1, is a 421 amino acid member of the class-I pyridoxal-phosphate-dependent aminotransferase family. Similar to glutamate-oxaloacetate transaminase (GOT1), GOT1L1 is found primarily as a homodimer in the cytoplasmic space but also has mitochondrial and chloroplastic isozymes. GOT1L1 transaminates 2-oxoglutarate with L-aspartate to yield oxaloacetate and L-glutamate. This reaction requires a pyridoxal phosphate cofactor to occur. The GOT1L1 peptidase is predominately expressed in the liver and serum levels of this protein can be used as an indicator of liver disease. Also, elevated glutamate concentrations in the brain interstitial fluids can lead to pathological brain conditions. The glutamate-scavenging properties of these aminotranferase type enzymes likely prevent glutamate excitotoxicity and the long-lasting neurological deficits seen after stroke.

Gen-ID: 137362