GDI1 Antikörper (AA 1-100)

Produktnummer ABIN1715018

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-GDI1 Antikörper wird verwendet zum Nachweis von GDI1 in Proben von Maus und Schimpanse. Er wurde validiert für ELISA, IF (cc), IF (p), IHC (p), IHC (fro) und ICC.

Kurzübersicht für GDI1 Antikörper (AA 1-100) (ABIN1715018)

Target: GDI1 (GDP Dissociation Inhibitor 1 (GDI1))

Reaktivität: Maus, Schimpanse

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GDI1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Produktdetails anti-GDI1 Antikörper

Bindungsspezifität: AA 1-100

Kreuzreaktivität: Schimpanse, Maus

Homologie: Human,Rat,Cow,Sheep,Pig,Rabbit,Zebrafish

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GDI1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-GDI1 Antikörper (ABIN1715018)

Zhang, Zhao, Zhang, Hao, Yu, Min, Li, Ma, Chen, Yi, Tang, Meng, Liu, Wang, Shen, Zhang: "Decrease in male mouse fertility by hydrogen sulfide and/or ammonia can Be inheritable." in: Chemosphere, Vol. 194, pp. 147-157, (2018) (PubMed).

Details zu GDI1

Target: GDI1 (GDP Dissociation Inhibitor 1 (GDI1))

Andere Bezeichnung: GDI1

Hintergrund:

Synonyms: 1A, FLJ41411, GDI-1, gdi1, GDIA_HUMAN, GDIL, GDP dissociation inhibitor 1, Guanosine diphosphate dissociation inhibitor 1, Mental retardation X-linked 41, Mental retardation X-linked 48, MRX41, MRX48, Oligophrenin 2, Oligophrenin-2, OPHN2, Protein XAP 4, Protein XAP-4, Protein XAP4, Rab GDI alpha, Rab GDP dissociation inhibitor alpha, RABGD1A, RABGDIA, XAP 4.

Background: Rab proteins, a family of Ras-related small GTP-binding proteins, play a key role in regulating intracellular vesicle trafficking (1?). Rab GDP dissociation inhibitor (Rab GDI or GDI2) forms a soluble complex with Rab proteins and thereby prevents the exchange of GDP for GTP (1?). In mammals, there exist two major isoforms, Rab GDI alpha (also known as XAP-4) and Rab GDI beta (1,4). While the mammalian Rab GDI beta-genes are ubiquitously expressed, the Rab GDI ?genes are predominantly brain-specific (1). Since it is expressed predominantly in neural and sensory tissues, Rab GDI a may serve a specific function in neural signal transmission (5). The gene sequences for the Rab GDI proteins are extremely conserved in evolution, with substantial homology preserved across three eukaryotic kingdoms (5).

Gen-ID: 2664