FAU Antikörper (AA 11-74)

Produktnummer ABIN1715004

Der Kaninchen Polyklonal anti-FAU Antikörper (ABIN1715004) detektiert spezifisch FAU in WB, IF (cc), IF (p), IHC (p) und IHC (fro). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für FAU Antikörper (AA 11-74) (ABIN1715004)

Target: FAU (Finkel-Biskis-Reilly Murine Sarcoma Virus (FBR-MuSV) Ubiquitously Expressed (FAU))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FAU Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-FAU Antikörper

Bindungsspezifität: AA 11-74

Verwendungszweck: FAU Polyclonal Antibody

Homologie: Human,Mouse,Rat,Cow,Sheep,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FAU

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB(1:300-5000),

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu FAU

Target: FAU (Finkel-Biskis-Reilly Murine Sarcoma Virus (FBR-MuSV) Ubiquitously Expressed (FAU))

Andere Bezeichnung: FAU/MNSF-beta

Hintergrund:

Synonyms: 40S ribosomal protein S30, asr1, FAU, FAU encoded ubiquitin like protein, FAU1, FBR MuSV associated ubiquitously expressed, Finkel Biskis Reilly murine sarcoma virus FBR MuSV ubiquitously expressed fox derived, Finkel Biskis Reilly murine sarcoma virus FBR MuSV ubiquitously expressed, Finkel Biskis Reilly murine sarcoma virus ubiquitously expressed, FLJ22986, Fub1, Fubi, MNSFbeta, Monoclonal nonspecic suppressor factor beta, Ribosomal protein S30, RPS30, S30, UBIM_HUMAN, Ubiquitin like protein fubi and ribosomal protein S30, Ubiquitin like protein fubi, Ubiquitin like S30 fusion protein, Ubiquitin-like protein FUBI.

Background: The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. The first step requires the ATP-dependent activation of the Ub C-terminus and the assembly of multi-Ub chains by the Ub-activating enzyme known as the E1 component. The Ub chain is then conjugated to the Ub-conjugating enzyme (E2) to generate an intermediate Ub-E2 complex. The Ub-ligase (E3) then catalyzes the transfer of Ub from E2 to the appropriate protein substrate. A wide range of enzymes facilitate in the proteolytic Ub pathway, including monoclonal nonspecific suppressor factor-beta (MNSF-beta), a subunit of MNSF, which is a lymphokine product of a murine T cell hybrid-oma that restricts the production of LPS-induced immunoglobulin secreting cells in an antigen-nonspecific manner. MNSF-beta is a ubiquitin-like fusion protein consisting of the ribosomal protein S30 and a protein that shares 36 % sequence identity with ubiquitin. This ubiquitin-like segment (Ubi-L) can be cleaved from MNSF-beta in the cytosol.

Gen-ID: 2197

UniProt: P62861