GNPDA2 Antikörper (AA 101-200)

Produktnummer ABIN1714817

Der Kaninchen Polyklonal Anti-GNPDA2-Antikörper wurde für WB, ELISA, IF (cc), IF (p), ICC, IHC (p) und IHC (fro) validiert. Er ist geeignet, GNPDA2 in Proben von Maus und Ratte zu detektieren.

Kurzübersicht für GNPDA2 Antikörper (AA 101-200) (ABIN1714817)

Target: GNPDA2 (Glucosamine-6-Phosphate Deaminase 2 (GNPDA2))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GNPDA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-GNPDA2 Antikörper

Bindungsspezifität: AA 101-200

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Dog,Cow,Sheep,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GNPDA2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu GNPDA2

Target: GNPDA2 (Glucosamine-6-Phosphate Deaminase 2 (GNPDA2))

Andere Bezeichnung: GNPDA2

Hintergrund:

Synonyms: GlcN6P deaminase 2, Glucosamine 6 phosphate deaminase 2, Glucosamine 6 phosphate isomerase 2, Glucosamine 6 phosphate isomerase SB52, Glucosamine-6-phosphate deaminase 2, Glucosamine-6-phosphate isomerase 2, Glucosamine-6-phosphate isomerase SB52, GNP2, GNPDA 2, Gnpda2, GNPI2_HUMAN, SB52.

Background: During fertilization in mammals, the sperm activates the egg by causing an increase in the level of free cytoplasmic calcium concentration. This increased calcium concentration induces a characteristic series of oscillations that trigger egg activation and early embryo development. A hamster protein named oscillin is thought to be involved in this pathway. The enzyme glucosamine-6-phosphate isomerase (GNPI) or deaminase (GNPDA1) and the related protein GNPDA2 are the human homologs of hamster oscillin. GNPDA1 and GNPDA2 catalyze the conversion of GNP to fructose-6-phosphate and ammonia. Both proteins exist as homohexamers and are ubiquitously expressed with highest expression in testis, ovary and heart. Three isoforms of GNPDA2 are expressed due to alternative splicing events.

Gen-ID: 132789