Glutathione Peroxidase 2 Antikörper (AA 41-140)

Produktnummer ABIN1714555

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Glutathione Peroxidase 2 in ELISA, WB, ICC, IHC (p), IF (cc), IF (p) und IHC (fro). Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für Glutathione Peroxidase 2 Antikörper (AA 41-140) (ABIN1714555)

Target: Glutathione Peroxidase 2 (GPX2)

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Glutathione Peroxidase 2 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-Glutathione Peroxidase 2 Antikörper

Bindungsspezifität: AA 41-140

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Cow,Sheep,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GPX2/Glutathione Peroxidase 2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu Glutathione Peroxidase 2

Target: Glutathione Peroxidase 2 (GPX2)

Andere Bezeichnung: GPX2/Glutathione Peroxidase 2

Hintergrund:

Synonyms: Gastrointestinal glutathione peroxidase, GI GPx, Glutathione peroxidase 2 gastrointestinal, Glutathione peroxidase 2, Glutathione peroxidase gastrointestinal, Glutathione peroxidase related protein 2, Glutathione peroxidase-gastrointestinal, Glutathione peroxidase-related protein 2, GPRP, GPRP-2, GPx 2, GPx-2, GPx-GI, GPX2, GPX2_HUMAN, GSHPx 2, GSHPx GI, GSHPx-2, GSHPx-GI.

Background: Glutathione peroxidase (GPx) enzymes are generally selenium-containing tetrameric glycoproteins that help prevent lipid peroxidation of cell membranes. GPx enzymes reduce lipid hydroperoxides to alcohols, and reduce free hydrogen peroxide to water. GPx members are among the few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by the nonsense (stop) codon TGA. There are eight GPx homologs (GPx-18). GPx-1 plays an important role in the antioxidant defense of the vascular wall and neural cells in response to oxidative stress. GPx-2 is the major isoform in the lungs and its basal or inducible expression is dependent on Nrf2. GPx-3 is under regulation by hypoxic stress and the expression and deficiency of GPx-3 is associated with cardiovascular disease and stroke. GPx-5 is selenium-independent, it is bound to the acrosome of sperm, where it may protect sperm from premature acrosome reaction in the epididymis.

Gen-ID: 2877

Pathways: Thyroid Hormone Synthesis