ABLIM3 Antikörper (AA 101-200)

Produktnummer ABIN1714485

Der Kaninchen Polyklonal anti-ABLIM3 Antikörper (ABIN1714485) detektiert spezifisch ABLIM3 in WB, IF, IHC (fro), IHC (p) und ICC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für ABLIM3 Antikörper (AA 101-200) (ABIN1714485)

Target: ABLIM3 (Actin Binding LIM Protein Family, Member 3 (ABLIM3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ABLIM3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Produktdetails anti-ABLIM3 Antikörper

Bindungsspezifität: AA 101-200

Verwendungszweck: ABLIM3 Polyclonal Antibody

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Cow,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ABLIM3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB(1:500-2000),

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu ABLIM3

Target: ABLIM3 (Actin Binding LIM Protein Family, Member 3 (ABLIM3))

Andere Bezeichnung: ABLIM3

Hintergrund:

Synonyms: abLIM-3, Ablim3, ABLM3_HUMAN, Actin binding LIM protein 3, Actin binding LIM protein family member 3, Actin-binding LIM protein 3, Actin-binding LIM protein family member 3, HMFN1661, KIAA0843.

Background: The ABLIM1 protein has an N-terminal domain that contains four double zinc finger motifs, which conform to the LIM motif consensus sequence. ABLIM1 binds to F-Actin through a dematin-like domain and is expressed in retina, brain and muscle tissue. There are four known isoforms of ABLIM1. The gene encoding ABLIM1 maps to a region of chromosome 10 associated with frequent loss of heterozygosity in human tumors, thus identifying ABLIM1 as a candidate tumor suppressor gene. ABLIM2 and ABLIM3 show highest expression in muscle and neuronal tissues, bind to F-Actin, and are localized on stress fibers. They also have been shown to enhance STARS (striated muscle activator of Rho signaling) dependent activation of serum-response factor (SRF), thereby modulating transcription.

Gen-ID: 22885