DNASEX Antikörper (AA 201-302)

Produktnummer ABIN1714436

Der Kaninchen Polyklonal anti-DNASEX Antikörper wird verwendet zum Nachweis von DNASEX in Proben von Human. Er wurde validiert für WB, IF (cc), IF (p), IHC (fro) und IHC (p).

Kurzübersicht für DNASEX Antikörper (AA 201-302) (ABIN1714436)

Target: DNASEX (Deoxyribonuclease X (DNASEX))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DNASEX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-DNASEX Antikörper

Bindungsspezifität: AA 201-302

Verwendungszweck: DNASE1L1 Polyclonal Antibody

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DNASE1L1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB(1:300-5000),

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu DNASEX

Target: DNASEX (Deoxyribonuclease X (DNASEX))

Andere Bezeichnung: DNASE1L1

Hintergrund:

Synonyms: Deoxyribonuclease I-like 1, Deoxyribonuclease I like 1, Deoxyribonuclease-1-like 1, DNAS1L1, DNase I like 1, DNase I like muscle specic, DNase I lysosomal like, DNase I-like 1, DNase X, DNASE1L1, DNASEX, DNL1L, DNSL1_HUMAN, Muscle specic DNase I like, DNASEX, Muscle-specic DNase I-like, XIB.

Background: DNASE1L1 is a 302 amino acid protein that localizes to the endoplasmic reticulum and belongs to the deoxyribonuclease family. Expressed at high levels in cardiac and skeletal muscle and at lower levels in a variety of tissues throughout the body, DNASE1L1 exists as multiple alternatively spliced isoforms and is thought to function in a similar manner to DNase l, possibly mediating internucleosomal DNA degradation via catalytic cleavage events. The gene encoding DNASE1L1 maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes. In conjunction with chromosome Y, chromosome X is responsible for sex determination. There are a number of conditions related to an abnormal number and combination of sex chromosomes, some of which include Turner's syndrome, color blindness, hemophilia and Duchenne muscular dystrophy.

Gen-ID: 1774