ATPase Inhibitory Factor 1 Antikörper (AA 26-106)

Produktnummer ABIN1714418

Der Kaninchen Polyklonal Anti-ATPase Inhibitory Factor 1-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, ATPase Inhibitory Factor 1 in Proben von Ratte zu detektieren.

Kurzübersicht für ATPase Inhibitory Factor 1 Antikörper (AA 26-106) (ABIN1714418)

Target: ATPase Inhibitory Factor 1 (ATPIF1)

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATPase Inhibitory Factor 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-ATPase Inhibitory Factor 1 Antikörper

Bindungsspezifität: AA 26-106

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ATPIF1/ATPase Inhibitory Factor 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu ATPase Inhibitory Factor 1

Target: ATPase Inhibitory Factor 1 (ATPIF1)

Andere Bezeichnung: ATP1/ATPase Inhibitory Factor 1

Hintergrund:

Synonyms: AT1_HUMAN, ATP synthase inhibitor protein, ATPase inhibitor, ATPase inhibitor mitochondrial, ATPase inhibitor protein, ATPase inhibitory factor 1, ATPI, ATP 1, ATP1, ATPIP, 1, 1, Inhibitor of F1Fo-ATPase, IP, MGC1167, MGC8898, mitochondrial.

Background: Mitochondrial ATP synthases (ATPases) transduce the energy contained in membrane electrochemical proton gradients into the energy required for synthesis of high-energy phosphate bonds. ATPases contain two linked complexes: F1, the hydrophilic catalytic core, and F0, the membrane-embedded protein channel. F1 consists of three Alpha chains and three Beta chains, which are weakly homologous, as well as one Gamma chain, one Delta chain and one Gamma chain. F0 consists of three subunits: a, b and c. A mitochondrial F1-ATPase inhibitor protein, ATPIF1 (ATPase inhibitory factor 1), also known as IP, IF1, ATPI or ATPIP (ATPase inhibitor protein), binds to the C-terminal region of a Beta subunit of the F1-ATPase at low pH values and, via interference of the Beta and Gamma subunit interaction, ATPIF1 regulates the activity of the F1F0-ATPase. This reversible ATPIF1 binding to F1F0-ATPase also occurs on the surface of endothelial cells.

Gen-ID: 93974