GCHFR Antikörper (AA 21-60)

Produktnummer ABIN1714314

Der Kaninchen Polyklonal anti-GCHFR Antikörper (ABIN1714314) detektiert spezifisch GCHFR in IF (cc), IF (p), IHC (p) und IHC (fro). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für GCHFR Antikörper (AA 21-60) (ABIN1714314)

Target: GCHFR (GTP Cyclohydrolase I Feedback Regulator (GCHFR))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GCHFR Antikörper ist unkonjugiert

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-GCHFR Antikörper

Bindungsspezifität: AA 21-60

Verwendungszweck: GCHFR Polyclonal Antibody

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Cow,Pig,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GCHFR

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu GCHFR

Target: GCHFR (GTP Cyclohydrolase I Feedback Regulator (GCHFR))

Andere Bezeichnung: GCHFR

Hintergrund:

Synonyms: GCHFR, GFRP, GFRP_HUMAN, GTP cyclohydrolase 1 feedback regulatory protein, GTP cyclohydrolase I feedback regulator, GTP cyclohydrolase I feedback regulatory protein, HsT16933, MGC138467, MGC138469, p35.

Background: GTP cyclohydrolase I feedback regulatory protein (GFRP) is encoded by the gene GCHFR. GFRP mediates feedback inhibition of GTP cyclohydrolase I activity by tetrahydrobiopterin. GFRP also acts as a mediator for the stimulatory effect of phenylalanine on enzyme activity. L-phenylalanine reverses this inhibition. The molecular weight of GFRP is approximately 9.5 kDa although cross-linking experiments have shown that GFRP is usually found as a homodimer or as a pentamer. 15q15.

Gen-ID: 2644