ARIH2 Antikörper (AA 41-140)

Produktnummer ABIN1714290

Dieses Anti-ARIH2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ARIH2 in WB, ELISA, IHC (p), ICC, IF (cc), IF (p) und IHC (fro). Geeignet für Human.

Kurzübersicht für ARIH2 Antikörper (AA 41-140) (ABIN1714290)

Target: ARIH2 (protein ariadne-2 homolog (ARIH2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARIH2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-ARIH2 Antikörper

Bindungsspezifität: AA 41-140

Homologie: Human,Mouse,Rat,Cow,Pig,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ARIH2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu ARIH2

Target: ARIH2 (protein ariadne-2 homolog (ARIH2))

Andere Bezeichnung: ARIH2

Hintergrund:

Synonyms: all trans retinoic acid inducible RING finger, Ari 2, Ari-2, ARI2, ARI2_HUMAN, Ariadne 2, Ariadne 2 protein homolog, ariadne homolog 2 Drosophila, ariadne homolog 2, ARIH 2, Arih2, E3 ubiquitin protein ligase ARIH2, E3 ubiquitin-protein ligase ARIH2, HT005, protein ariadne 2 homolog, Protein ariadne-2 homolog, Triad 1, TRIAD1, Triad1 protein, UIP48.

Background: TRIAD1, also known as ARIH2 (ariadne homolog 2) or ARI2, is a 493 amino acid protein that contains one IBR-type zinc finger and two RING-type zinc fingers and belongs to the ariadne subfamily of RBR proteins. Localized to the nucleus, TRIAD1 interacts with UBE2L3 and is thought to act as an E3 ubiquitin-protein ligase, functioning to accept ubiquitin from E2 ubiquitin-conjugating enzymes and transfer the acquired ubiquitin residue to target substrates. TRIAD1 is subject to post-translational DNA damage-dependent phosphorylation, probably by ATM or ATR. The gene encoding TRIAD1 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci.

Gen-ID: 10425