AQP2 Antikörper (pSer256)

Produktnummer ABIN1714244

Der Kaninchen Polyklonal Anti-AQP2-Antikörper wurde für WB, IF (p) und IHC (p) validiert. Er ist geeignet, AQP2 in Proben von Human, Ratte und Maus zu detektieren.

Kurzübersicht für AQP2 Antikörper (pSer256) (ABIN1714244)

Target: AQP2 (Aquaporin 2 (Collecting Duct) (AQP2))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AQP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-AQP2 Antikörper

Bindungsspezifität: pSer256

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human AQP2 around the phosphorylation site of Ser256

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: (1:100-1000), IHC-P: (1:100-500), IF(IHC-P): (1:50-200)
Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu AQP2

Target: AQP2 (Aquaporin 2 (Collecting Duct) (AQP2))

Andere Bezeichnung: Aqp2

Hintergrund:

Synonyms: Aquaporin 2 phospho S256, Aquaporin 2 phospho Ser256, p-Aquaporin 2 phospho S256, p-Aquaporin 2 S256, ADH water channel, AQP 2, AQP CD, AQP2, AQPCD, Aquaporin 2 collecting duct, Aquaporin CD, Aquaporin2, Aquaporine 2, Collecting duct water channel protein, MGC34501, Water channel protein for renal collecting duct, WCH CD, WCHCD, AQP2_HUMAN.

Background: Aquaporins (AQPs) are a large family of integral membrane water transport channel proteins that facilitate the transport of water through the cell membrane. This function is conserved in animals, plants and bacteria. Many isoforms of aquaporin have been identified in mammals, designated AQP0 through AQP10. Aquaporins are widely distributed and it is not uncommon for more than one type of AQP to be present in the same cell. Although most aquaporins are only permeable to water, AQP3, AQP7, AQP9 and one of the two AQP10 transcripts are also permeable to urea and glycerol. AQP2 is the only water channel that is activated by vasopressin to enhance water reabsorption in the kidney collecting duct. Aquaporins are involved in renal water absorption, generation of pulmonary secretions, lacrimation, and the secretion and reabsorption of cerebrospinal fluid and aqueous humor.

Gen-ID: 359

Pathways: Response to Water Deprivation