IP3 Receptor Antikörper (AA 110-160)
Kurzübersicht für IP3 Receptor Antikörper (AA 110-160) (ABIN1714206)
Target
Alle IP3 Receptor (ITP-R83A) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 110-160
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Kreuzreaktivität
- Human, Maus, Ratte
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human IP3 Receptor
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Isotyp
- IgG
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Applikationshinweise
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IHC-P 1:200-400
IF(IHC-P) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Haltbarkeit
- 12 months
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- IP3 Receptor (ITP-R83A) (Inositol 1,4,5,-Tris-Phosphate Receptor (ITP-R83A))
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Andere Bezeichnung
- IP3 Receptor
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Hintergrund
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Synonyms: ACV, CLA4, IP3R, IP3R1, SCA15, SCA16, SCA29, INSP3R1, PPP1R94, Inositol 1,4,5-trisphosphate receptor type 1, IP3 receptor isoform 1, IP3R 1, Type 1 inositol 1,4,5-trisphosphate receptor, Type 1 InsP3 receptor, ITPR1
Background: Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).
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Gen-ID
- 3708
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UniProt
- Q14643
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Pathways
- Fc-epsilon Rezeptor Signalübertragung, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
Target
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