HDAC5 Antikörper (pSer498)

Produktnummer ABIN1714080

Dieses Anti-HDAC5-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von HDAC5 in WB, IHC (p) und IF (p). Geeignet für Human, Maus, Ratte, Rind (Kuh), Hund und Huhn.

Kurzübersicht für HDAC5 Antikörper (pSer498) (ABIN1714080)

Target: HDAC5 (Histone Deacetylase 5 (HDAC5))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Huhn

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HDAC5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-HDAC5 Antikörper

Bindungsspezifität: pSer498

Kreuzreaktivität: Rind (Kuh), Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human HDAC5 around the phosphorylation site of Ser498

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB (1:100-500),IHC-P (1:100-500),IF (p) (1:100-500)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu HDAC5

Target: HDAC5 (Histone Deacetylase 5 (HDAC5))

Andere Bezeichnung: HDAC5

Hintergrund:

Synonyms: HDAC5Ser498, HDAC5S498, p-HDAC5Ser498, p-HDAC5S498, HD 5, HD5, HDAC 5, Histone deacetylase 5, KIAA0600, NY CO 9, Antigen NY CO 9, FLJ90614, HDAC5_HUMAN, Antigen NY-CO-9.

Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Monocarboxylic Acid Catabolic Process