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DMAP1 Antikörper (AA 31-130)

Dieses Anti-DMAP1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von DMAP1 in ELISA, IHC (p), ICC, IF (cc), IF (p) und IHC (fro). Geeignet für Xenopus laevis.
Produktnummer ABIN1714047

Kurzübersicht für DMAP1 Antikörper (AA 31-130) (ABIN1714047)

Target

Alle DMAP1 Antikörper anzeigen
DMAP1 (DNA Methyltransferase 1-Associated Protein 1 (DMAP1))

Reaktivität

  • 39
  • 15
  • 13
  • 10
  • 8
  • 7
  • 7
  • 6
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
Xenopus laevis

Wirt

  • 31
  • 4
  • 4
Kaninchen

Klonalität

  • 33
  • 6
Polyklonal

Konjugat

  • 30
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser DMAP1 Antikörper ist unkonjugiert

Applikation

  • 30
  • 12
  • 7
  • 6
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 31-130

    Kreuzreaktivität

    Xenopus laevis

    Homologie

    Human,Mouse,Rat,Dog,Cow,Sheep,Chicken,Rabbit

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human DMAP1

    Isotyp

    IgG
  • Applikationshinweise

    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Haltbarkeit

    12 months
  • Target

    DMAP1 (DNA Methyltransferase 1-Associated Protein 1 (DMAP1))

    Andere Bezeichnung

    DMAP1

    Hintergrund

    Synonyms: DKFZp686L09142, DMAP 1, DNA methyltransferase 1-associated protein 1, DNMAP 1, DNMAP1, DNMT1-associated protein 1, DNMT1-associated protein 1, DNMTAP 1, DNMTAP1, EAF 2, EAF2, FLJ11543, KIAA1425, MAT 1-mediated transcriptional repressor, MGC55593, SWC 4, SWC4, zgc:55593.

    Background: Methylation of DNA contributes to the regulation of gene transcription in eukaryotic systems. DNA methylation is predominantly found on cytosine residues that are present in dinucleotide motifs consisting of a 5' cytosine followed by a guanosine (CpG), and it requires the enzymatic activity of DNA methyltransferases (DNMTs), which results in transcriptional repression of the methylated gene. DNA methyltransferase 1-associating protein (Dmap1) binds to methyl-CpG rich domains and mediate the transcriptional inhibition associated with DNA methylation. Dmap1 interacts with Daxx to enhanced Daxx-mediated repression of glucocorticoid receptor transcriptional activity. Daxx also protects Dmap1 from protein degradation in vivo.

    Gen-ID

    55929
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