FBXO45 Antikörper (AA 110-210)

Produktnummer ABIN1714025

Der Kaninchen Polyklonal Anti-FBXO45-Antikörper wurde für ELISA, WB, ICC, IF (cc), IF (p), IHC (fro) und IHC (p) validiert. Er ist geeignet, FBXO45 in Proben von Maus und Ratte zu detektieren.

Kurzübersicht für FBXO45 Antikörper (AA 110-210) (ABIN1714025)

Target: FBXO45 (F-Box Protein 45 (FBXO45))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBXO45 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-FBXO45 Antikörper

Bindungsspezifität: AA 110-210

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Dog,Sheep,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FBXO45

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu FBXO45

Target: FBXO45 (F-Box Protein 45 (FBXO45))

Andere Bezeichnung: FBXO45

Hintergrund:

Synonyms: F box protein 45, F-box only protein 45, F-box/SPRY domain-containing protein 1, FBSP1_HUMAN, FBX45, fbxo45, hFbxo45.

Background: Belonging to the F-box family of proteins, FBXO45 is a 286 amino acid protein that contains one C-terminal F-box domain. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein)-type E3 ubiquitin ligase complex and are involved in substrate recognition and protein recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular mechanisms, including the cell cycle, the immune response, signaling cascades and developmental processes. They function by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, IB- and -catenin, for degradation by the proteasome after ubiquitination. Via its F-box domain, FBXO45 can directly interact with Skp1 p19 and CUL-1. FBXO45 has been shown to be an estrogen-induced gene.

Gen-ID: 200933

UniProt: P0C2W1