TESK2 Antikörper (AA 301-400)

Produktnummer ABIN1713977

Der Kaninchen Polyklonal Anti-TESK2-Antikörper wurde für WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) und ICC validiert. Er ist geeignet, TESK2 in Proben von Human zu detektieren.

Kurzübersicht für TESK2 Antikörper (AA 301-400) (ABIN1713977)

Target: TESK2 (Testis-Specific Kinase 2 (TESK2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TESK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Produktdetails anti-TESK2 Antikörper

Bindungsspezifität: AA 301-400

Homologie: Human,Mouse,Rat,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TESK2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu TESK2

Target: TESK2 (Testis-Specific Kinase 2 (TESK2))

Andere Bezeichnung: TESK2

Hintergrund:

Synonyms: Dual specicity testis specic protein kinase 2, Dual specicity testis-specic protein kinase 2, MGC29168, OTTHUMP00000009093, RP23-109A3.2, Tesk2, TESK2_HUMAN, Testicular protein kinase 2, Testis specic kinase 2.

Background: TESK2 is a nuclear protein that belongs to the protein kinase superfamily and is expressed in testis and prostate. Functioning as a dual-specificity protein kinase, TESK2 catalyzes the ATP-dependent phosphorylation of substrates and autophosphorylation on tyrosine and serine/threonine residues, thereby mediating intracellular signal transduction pathways. TESK2 requires magnesium as a cofactor and its catalytic activity is thought to play an important role in meiotic events such as spermatogenesis. TESK2 contains one protein kinase domain that is 65 % identical to the kinase domain found in TESK1 (testicular protein kinase 1), suggesting a similar role for these proteins in phosphorylation events. Three isoforms of TESK2 are expressed due to alternative splicing.

Gen-ID: 10420

Pathways: Cell-Cell Junction Organization