FHOD1 Antikörper (pThr1141)

Produktnummer ABIN1713963

Dieses Anti-FHOD1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von FHOD1 in WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) und ICC. Geeignet für Human und Ratte.

Kurzübersicht für FHOD1 Antikörper (pThr1141) (ABIN1713963)

Target: FHOD1 (Formin Homology 2 Domain Containing 1 (FHOD1))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FHOD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Produktdetails anti-FHOD1 Antikörper

Bindungsspezifität: pThr1141

Kreuzreaktivität: Human, Ratte

Homologie: Mouse,Dog,Cow,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human FHOD1 around the phosphorylation site of Thr1141

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu FHOD1

Target: FHOD1 (Formin Homology 2 Domain Containing 1 (FHOD1))

Andere Bezeichnung: FHOD1

Hintergrund:

Synonyms: FHOD1 phospho T1141, p-FHOD1 phospho T1141, FH1/FH2 domain containing protein, FH1/FH2 domain-containing protein 1, Fhod1, FHOD1_HUMAN, FHOS, FHOS1, Formin homolog overexpressed in spleen 1, Formin homology 2 domain containing 1, Formin homology 2 domain containing protein 1, Formin homology 2 domain-containing protein 1.

Background: The limb deformity (ld) locus influences normal limb development and gives rise to alternative mRNAs that can translate into a family of protein products known as formins. Formins play a crucial role in cytoskeletal reorganization by influencing actin filament assembly. The temporal genetic hierarchy influencing normal limb development can deregulate and mediate mammalian developmental syndromes. FHOD1 induces the formation of and associates with bundled actin stress fibers in response to the activity of the Rho-ROCK cascade. It influences several cellular activities including cell migration, cytoskeletal arrangement, signal transduction and gene expression.

Gen-ID: 29109