alpha Adducin Antikörper (pThr445)
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- Target Alle alpha Adducin (ADD1) Antikörper anzeigen
- alpha Adducin (ADD1) (Adducin 1 (Alpha) (ADD1))
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Bindungsspezifität
- pThr445
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser alpha Adducin Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Homologie
- Human,Mouse,Rat
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic phosphopeptide derived from human alpha Adducin around the phosphorylation site of Thr445
- Isotyp
- IgG
- Top Product
- Discover our top product ADD1 Primärantikörper
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- Applikationshinweise
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- alpha Adducin (ADD1) (Adducin 1 (Alpha) (ADD1))
- Andere Bezeichnung
- alpha Adducin (ADD1 Produkte)
- Synonyme
- ADDA antikoerper, AI256389 antikoerper, alpha-adducin antikoerper, bZ1H20.1 antikoerper, cb787 antikoerper, zgc:158352 antikoerper, add2 antikoerper, adda antikoerper, add1-a antikoerper, ADD1 antikoerper, adducin 1 antikoerper, adducin 1 (alpha) antikoerper, adducin 1 S homeolog antikoerper, ADD1 antikoerper, Add1 antikoerper, add1 antikoerper, add1.S antikoerper
- Hintergrund
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Synonyms: Adducin phospho T445, p-Adducin phospho T445, ADD1, ADDA, Adducin 1 alpha, Adducin 1, Alpha adducin, ADDA_HUMAN.
Background: Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha and beta adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha and gamma adducins are ubiquitously expressed. In contrast, beta adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca2+/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms, however, not all variants have been fully described.
- Gen-ID
- 118
- UniProt
- P35611
- Pathways
- Negative Regulation of Hormone Secretion, Regulation of Actin Filament Polymerization, Regulation of Lipid Metabolism by PPARalpha, ER-Nucleus Signaling
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