PRELP Antikörper (AA 151-250)

Produktnummer ABIN1713885

Dieses Anti-PRELP-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PRELP in IHC (p) und IHC (fro). Geeignet für Human.

Kurzübersicht für PRELP Antikörper (AA 151-250) (ABIN1713885)

Target: PRELP (Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRELP Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-PRELP Antikörper

Bindungsspezifität: AA 151-250

Homologie: Human,Mouse,Rat,Cow,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PRELP

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu PRELP

Target: PRELP (Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP))

Andere Bezeichnung: PRELP

Hintergrund:

Synonyms: 55 kDa leucine rich repeat protein of articular cartilage, MST161, MSTP161, Prelp, PRELP_HUMAN, Prolargin, Prolargin proteoglycan, Proline arginine rich end leucine rich repeat protein, Proline-arginine-rich end leucine-rich repeat protein, Proline/arginine rich end leucine rich repeat protein, SLRR2A.

Background: PRELP (proline/arginine-rich end leucine-rich repeat protein), also known as Prolargin, MST161, SLRR2A or MSTP161, is a 382 amino acid secreted protein that localizes to the extracellular matrix. Belonging to the Class II subfamily of the small leucine-rich proteoglycan (SLRP) family, PRELP contains twelve LRR (leucine-rich) repeats, which are motifs consisting of 20-29 residues that are present in numerous proteins with diverse functions and provide versatile structural framework for the formation of protein-protein interactions. Highly expressed in cartilage, basement membranes and developing bone, PRELP is considered a glycosaminoglycan (GAG)- and collagen-binding anchor protein that associates with the basement membrane heparan sulfate proteoglycan perlecan. PRELP acts as a linker between the extracellular matrix and the cell surface of proteoglycans and may be partially responsible for Hutchinson-Gilford progeria (HGP), an extremely rare genetic disorder that causes premature, rapid aging shortly after birth.

Pathways: Glycosaminoglycan Metabolic Process