ARHGAP15 Antikörper (AA 201-300)

Produktnummer ABIN1713703

Produktdetails anti-ARHGAP15 Antikörper

Target: ARHGAP15 (rho GTPase Activating Protein 15 (ARHGAP15))

Bindungsspezifität: AA 201-300

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARHGAP15 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ARHGAP15

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu ARHGAP15

Target: ARHGAP15 (rho GTPase Activating Protein 15 (ARHGAP15))

Andere Bezeichnung: ARHGAP15 (ARHGAP15 Produkte)

Synonyme: pp905 antikoerper, sh3d20 antikoerper, sh3p20 antikoerper, camgap1 antikoerper, BM046 antikoerper, 5830480G12Rik antikoerper, Rho GTPase activating protein 15 antikoerper, Rho GTPase activating protein 27 antikoerper, ARHGAP15 antikoerper, arhgap27 antikoerper, Arhgap15 antikoerper

Hintergrund:

Synonyms: ArhGAP15, BM046, Rho GTPase activating protein 15, Rho type GTPase activating protein 15, RHG15_HUMAN.

Background: Rho GTPases, which play fundamental roles in numerous cellular processes, are initiated by external stimuli that signal though G-protein coupled receptors. ARHGEF15 (Rho guanine nucleotide exchange factor (GEF) 15), also known as ARGEF15 or Vsm-RhoGEF, is a 841 amino acid protein expressed in the vascular smooth muscle of coronary artery. ARHGEF15 functions as a specific guanine nucleotide exchange factor for RhoA and interacts with ephrin-A4 in vascular smooth muscle cells. Containing one DH (DBL-homology) domain, ARHGEF15 is phosphorylated on tyrosine residues upon ephrin-A1 stimulation. The DH domain consists of a region of about 150 amino acids that induces Rho family GTPases to release GDP. This effectively activates the Rho GTPase by allowing GTP binding. ARHGEF15 is encoded by a gene located on human chromosome 17, which comprises over 2.5 % of the human genome and encodes over 1,200 genes.

Gen-ID: 55843