c-Rel Antikörper (pSer503)

Produktnummer ABIN1713673

This anti-c-Rel antibody (ABIN1713673) is a Rabbit Polyclonal antibody detecting c-Rel in WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro). Suitable for Human.

Kurzübersicht für c-Rel Antikörper (pSer503) (ABIN1713673)

Target: c-Rel (REL proto-oncogene (c-Rel))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser c-Rel Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-c-Rel Antikörper

Bindungsspezifität: pSer503

Kreuzreaktivität: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human C-REL around the phosphorylation site of Ser503

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-c-Rel Antikörper (ABIN1713673)

Lee, Lee, Kim, Kim, Yang, Jeong, Seong: "Radiation Inhibits Interleukin-12 Production via Inhibition of C-Rel through the Interleukin-6/ Signal Transducer and Activator of Transcription 3 Signaling Pathway in Dendritic Cells." in: PLoS ONE, Vol. 11, Issue 1, pp. e0146463, (2016) (PubMed).

Details zu c-Rel

Target: c-Rel (REL proto-oncogene (c-Rel))

Andere Bezeichnung: C-REL

Hintergrund:

Synonyms: c-Rel phospho S503, c-Rel phospho Ser503, p-c-Rel phospho S503, p-c-Rel S503, Avian reticuloendotheliosis, C REL, C Rel protein, c Rel proto oncogene protein, Oncogene REL, Oncogene REL avian reticuloendotheliosis, REL, v rel avian reticuloendotheliosis viral oncogene homolog, v rel reticuloendotheliosis viral oncogene homolog.

Background: The REL gene encodes c-Rel, a transcription factor that is a member of the Rel/NFKB family, which also includes RELA (MIM 164014), RELB (604758), NFKB1 (MIM 164011), and NFKB2 (MIM 164012). These proteins are related through a highly conserved N-terminal region termed the 'Rel domain,' which is responsible for DNA binding, dimerization, nuclear localization, and binding to the NFKB inhibitor (MIM 164008) (Belguise and Sonenshein, 2007 [PubMed 18037997]).[supplied by OMIM, May 2008].

Gen-ID: 5966

UniProt: Q04864