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Hect E3 Ubiquitin Ligase Antikörper (AA 1-100)

Der Kaninchen Polyklonal Anti-Hect E3 Ubiquitin Ligase-Antikörper wurde für ELISA, ICC, IF (cc), IF (p), IHC (fro) und IHC (p) validiert. Er ist geeignet, Hect E3 Ubiquitin Ligase in Proben von Ratte zu detektieren.
Produktnummer ABIN1713527

Kurzübersicht für Hect E3 Ubiquitin Ligase Antikörper (AA 1-100) (ABIN1713527)

Target

Hect E3 Ubiquitin Ligase (LOC662402)

Reaktivität

Ratte

Wirt

Kaninchen

Klonalität

Polyklonal

Applikation

ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Bindungsspezifität

    AA 1-100

    Kreuzreaktivität

    Ratte

    Homologie

    Human

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human HECT E3 ubiquitin ligase

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Haltbarkeit

    12 months
  • Target

    Hect E3 Ubiquitin Ligase (LOC662402)

    Andere Bezeichnung

    HECT E3 ubiquitin ligase

    Hintergrund

    Synonyms: CEB1, CEBP1, Cyclin E binding protein 1, Cyclin-E-binding protein 1, E3 ISG15--protein ligase HERC5, HECT domain and RCC1 like domain containing protein 5, HECT domain and RCC1-like domain-containing protein 5, Hect domain and RLD 5, HECT E3 ubiquitin ligase, HERC5, HERC5_HUMAN, Herc6.

    Background: HECT E3 ubiquitin ligase is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4.

    Gen-ID

    51191
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