Claudin 7 Antikörper (PE)

Produktnummer ABIN1712744

Der Kaninchen Polyklonal anti-Claudin 7 Antikörper wird verwendet zum Nachweis von Claudin 7 in Proben von Human, Maus, Ratte, Hund und Rind (Kuh). Er wurde validiert für IF (p).

Kurzübersicht für Claudin 7 Antikörper (PE) (ABIN1712744)

Target: Claudin 7 (CLDN7)

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Claudin 7 Antikörper ist konjugiert mit PE

Applikation: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-Claudin 7 Antikörper (PE)

Kreuzreaktivität: Maus, Ratte (Rattus), Hund, Rind (Kuh)

Aufreinigung: purified by Protein A

Immunogen: KLH conjugated synthetic peptide derived from human Claudin 7

Isotyp: IgG

Anwendungsinformationen

Kommentare:

Excitation / Emission wavelength: 496nm / 578nm

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 µg/µL

Buffer: Aqueous buffered solution containing 100 µg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 4 °C for 12 months

Haltbarkeit: 12 months

Details zu Claudin 7

Target: Claudin 7 (CLDN7)

Andere Bezeichnung: Claudin 7

Hintergrund: The Claudin superfamily consists of many structurally related proteins in humans (1). These proteins are important structural and functional components of tight junctions in paracellular transport (1,2). Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues (1). Three classes of proteins are known to localize to tight junctions, including the Claudins, Occludin and Junction adhesion molecule (3). Claudins, which consist of four transmembrane domains and two extracellular loops make up tight junction strands (4). Claudin expression is highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions (5). mRNA studies indicate that Claudin-7 is specifically expressed in mouse lung and kidney, but not in heart, brain, spleen, liver, skeletal muscle or testis (6). The gene encoding human Claudin-7 maps to chromosome 17p13 (7).

Gen-ID: 1366

Pathways: Hepatitis C