Stabilin 2 (STAB2) Antikörper (PE)

Produktnummer ABIN1712724

Dieses Anti--Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von in FACS. Geeignet für Human, Maus und Ratte.

Kurzübersicht für Stabilin 2 (STAB2) Antikörper (PE) (ABIN1712724)

Target: Stabilin 2 (STAB2)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: PE

Applikation: Flow Cytometry (FACS)

Produktdetails

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Stabilin-2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM(1:20-100)

Kommentare:

Exitation/Emission: 480,565nm/578nm

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at 4°C

Haltbarkeit: 12 months

Antigendetails

Target: Stabilin 2 (STAB2)

Andere Bezeichnung: Stabilin 2/STAB 2

Hintergrund:

Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Hyaluronan receptor that binds to and mediates endocytosis of hyaluronic acid (HA). Acts also, in different species, as a primary systemic scavenger receptor for heparin (Hep), chondroitin sulfate (CS), dermatan sulfate (DS), nonglycosaminoglycan (GAG), acetylated low-density lipoprotein (AcLDL), pro-collagen propeptides and advanced glycation end products (AGE). May serve to maintain tissue integrity by supporting extracellular matrix turnover or it may contribute to maintaining fluidity of bodily liquids by resorption of hyaluronan. Counter receptor which plays an important role in lymphocyte recruitment in the hepatic vasculature. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. The proteolytically processed 190 kDa form also functions as an endocytosis receptor for heparin internalisation as well as HA and CS.

Subcellular location: Extracellular

Synonyms: FEX2, HARE, FEEL2, FELL2, FELE-2, Stabilin-2, FAS1 EGF-like and X-link domain-containing adhesion molecule 2, Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 2, FEEL-2, Hyaluronan receptor for endocytosis, STAB2, FELL

Gen-ID: 55576

UniProt: Q8WWQ8

Pathways: Glycosaminoglycan Metabolic Process