BOC Antikörper (PE)

Produktnummer ABIN1712708

Der Kaninchen Polyklonal Anti-BOC-Antikörper wurde für FACS validiert. Er ist geeignet, BOC in Proben von Human, Ratte und Maus zu detektieren.

Kurzübersicht für BOC Antikörper (PE) (ABIN1712708)

Target: BOC (Brother Of CDO (BOC))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BOC Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Produktdetails anti-BOC Antikörper (PE)

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Protein BOC

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM: 1:20-100
Optimal working dilution should be determined by the investigator.

Kommentare:

Exitation/Emission: 480,565nm/578nm

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at 4 °C

Haltbarkeit: 12 months

Details zu BOC

Target: BOC (Brother Of CDO (BOC))

Andere Bezeichnung: Protein Boc

Hintergrund:

BOC is a receptor-like, single pass membrane protein belonging to the cell surface molecule subfamily of the Immunoglobulin/fibronectin type-III repeat family within the immunoglobulin superfamily. It contains three fibronectin type-III domains and four Immunoglobulin-like C2-type domains in its extracellular region. The intracellular region of BOC is not required for proper function. BOC localizes to the cell membrane and is ubiquitously expressed with highest expression levels in skeletal muscle and small intestine. Its mRNA expression is down-regulated by Ras. BOC is involved in accelerating myoblast differentiation and is dependent on CDO for its activity. BOC and CDO are co-expressed in muscle precursors and are components of a receptor complex that mediates cell-cell interactions important in myogenesis. Overexpression of BOC results in enhanced differentiation of myoblast cells. In addition, BOC is a target and signaling component of the Shh pathway.

Subcellular location: Extracellular

Synonyms: Boc homolog mouse, Brother of CDO, Protein BOC, brother of CDO precursor, Protein BOC, BOC_HUMAN.

Gen-ID: 91653

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development