Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

GLI4 Antikörper (AA 271-376) (HRP)

This anti-GLI4 antibody (ABIN1712537) is a Rabbit Polyclonal antibody detecting GLI4 in WB, ELISA, IHC (p), IHC (fro). Suitable for Human.
Produktnummer ABIN1712537

Quick Overview for GLI4 Antikörper (AA 271-376) (HRP) (ABIN1712537)

Target

Alle GLI4 Antikörper anzeigen
GLI4 (GLI Family Zinc Finger Protein 4 (GLI4))

Reaktivität

  • 34
  • 1
  • 1
Human

Wirt

  • 30
  • 4
Kaninchen

Klonalität

  • 31
  • 3
Polyklonal

Konjugat

  • 13
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser GLI4 Antikörper ist konjugiert mit HRP

Applikation

  • 28
  • 13
  • 13
  • 13
  • 4
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 14
    • 8
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 271-376

    Kreuzreaktivität

    Human

    Homologie

    Mouse,Rat,Cow,Pig,Horse

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human GLI4

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Handhabung

    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    GLI4 (GLI Family Zinc Finger Protein 4 (GLI4))

    Andere Bezeichnung

    GLI4

    Hintergrund

    Synonyms: GLI 4, GLI Kruppel family member GLI 4, GLI Kruppel family member GLI4, GLI4, GLI4_HUMAN, HKR 4, HKR4, HKR4 protein, Krueppel related zinc finger protein 4, Krueppel-related zinc finger protein 4, Neural specic DNA binding protein, Oncogene HKR 4, Oncogene HKR4, Protein HKR 4, Protein HKR4, Zinc finger protein GLI 4, Zinc finger protein GLI4.

    Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a krueppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. GLI-4, also known as HKR4, is a 376 amino acid protein that localizes to the nucleus and contains seven C2H2-type zinc fingers. Belonging to the krueppel C2H2-type zinc-finger protein family, GLI-4 may function as a transcriptional regulator, effectively activating or repressing the transcription of target genes. The gene encoding GLI-4 maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies.

    Gen-ID

    2738
Sie sind hier:
Chat with us!